EPSPs in rat neocortical neurons in vitro. I. Electrophysiological evidence for two distinct EPSPs
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چکیده
منابع مشابه
Lack of monosynaptic corticomotoneuronal EPSPs in rats: disynaptic EPSPs mediated via reticulospinal neurons and polysynaptic EPSPs via segmental interneurons.
In the rat, some findings have been taken to suggest the existence of monosynaptic corticomotoneuronal (CM) connections. Because this connection is believed to be largely responsible for the ability to make independent digit movements in primates and man, it has been inferred that the monosynaptic CM connection in the rat is likewise important for skilled prehension. Comparison of intra- and ex...
متن کاملElectrophysiological properties of neocortical neurons in vitro.
1. Intracellular recordings were obtained from neurons of the guinea pig sensorimotor cortical slice maintained in vitro. Under control recording conditions input resistances, time constants, and spiking characteristics of slice neurons were well within the ranges reported by other investigators for neocortical neurons in situ. However, resting potentials (mean of -75 mV) and spike amplitudes (...
متن کاملLinear to supralinear summation of AMPA-mediated EPSPs in neocortical pyramidal neurons.
It has been hypothesized that voltage-sensitive conductances present on the dendrites of neurons can influence summation of excitatory postsynaptic potentials (EPSPs) and hence affect how neurons compile information. Greater than linear summation of EPSPs has been postulated to facilitate coincidence detection by cortical neurons. This study examined whether the summation of subthreshold AMPA-m...
متن کاملAmplification of EPSPs by axosomatic sodium channels in neocortical pyramidal neurons
Simultaneous somatic and dendritic recordings were made from the same neocortical layer V pyramidal neuron, and current injection via the dendritic recording pipette was used to simulate the voltage change that occurs during an EPSP. At the soma, these simulated EPSPs increased nonlinearly with the amplitude of the dendritic current injection and with depolarization of the membrane potential. B...
متن کاملLack of monosynaptic corticomotoneuronal EPSPs in rats: disynaptic EPSPs mediated via reticulospinal neurones and polysynaptic EPSPs via segmental interneurones
In the rat, some findings have been taken to suggest the existence of monosynaptic cortico-motoneuronal (CM) connections. Since this connection is believed to be largely responsible for the ability to make independent digit movements in primates and man, it has been inferred that the monosynaptic CM connection in the rat is likewise important for skilled prehension. Comparison of intraand extra...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 1989
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.1989.61.3.607